In vertebrates oocytes undergo a series of maturation steps arresting at metaphase Ⅱ, and can then be fertilized by a s......

The status of histone lysine methylation regulates the gene expression.Lysine-sepcific demethylase(KDM),as one group of ......

Long Noncoding RNA (lncRNA) is a kind of non-protein coding transcripts longer than 200 nucleotides, and plays important......

During the process of embryonic development in mammals,epigenetic modifications must be erased and reconstructed.In part......

Objective: Histone modification is an important epigenetic modification,which plays an important role in regulation of g......

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Natural products generally fall into the biologically relevant chemical space and always possess novel biological activi......